Search results for "Single injection"

showing 3 items of 3 documents

Antiaggressive and motor effects of haloperidol show different temporal patterns in the development of tolerance.

1993

Abstract The study of the temporal course of tolerance development was used as a means to separate different aspects of the action of haloperidol on social behavior. Agonistic behavior was studied in isolated male mice that confronted standard opponents (anosmic and grouped conspecifics) in a neutral area. The aggressive and motor behaviors of the experimental animals were evaluated 30 min or 24 h either after a single injection of haloperidol (0.4 mg/kg) or following the last of a series of 15 or 30 injections. When animals were evaluated 30 min after the haloperidol injection, no tolerance to the antiaggressive effects was evident. The action on immobility, on the contrary, showed a clear…

MaleMale miceExperimental and Cognitive PsychologyPharmacologyMotor ActivityDrug Administration ScheduleBehavioral NeuroscienceMiceNeural PathwaysAgonistic behaviourHaloperidolmedicineAnimalsDose-Response Relationship DrugDrug administrationBrainSingle injectionHaloperidol injectionBehavioral analysisAggressionHaloperidolPsychologyArousalNeuroscienceAgonistic Behaviormedicine.drugPhysiologybehavior
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Die Wirkung von Harmalin auf die Konzentration von Noradrenalin und Adrenalin im Herzen

1959

A single injection of harmaline increases the noradrenaline and adrenaline concentration in the rat heart. The maximum effect is obtained after about 40 min.

PharmacologyHeart pharmacologyChemistryCell BiologyRat heartSingle injectionPharmacologyCellular and Molecular NeuroscienceHarmalinechemistry.chemical_compoundEpinephrine metabolismMolecular MedicineNorepinephrine metabolismMolecular BiologyExperientia
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Renale Wasser- und Elektrolytausscheidung durstender Ratten innerhalb von 32 Stunden nach einmaliger intraven�ser Gabe von Chlormerodrin oder Mersalyl

1959

At the beginning of a period of hunger and thirst, rats received 3 or 4,5 to 5 mg.Hg/kg. as chlormerodrine or mersalyl. The optimal dose of 3mg Hg/kg.as chlormerodrine or 4,5mg. Hg/kg. as mersalyl was effective for more than 32 hours after a single injection.

PharmacologyIntravenous dosebusiness.industryGeneral MedicineSingle injectionPharmacologyElectrolyte excretionMersalylThirstchemistry.chemical_compoundchemistryChlormerodrineRenal physiologyMedicineChlormerodrinmedicine.symptombusinessNaunyn-Schmiedeberg's Archiv f�r Experimentelle Pathologie und Pharmakologie
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